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Allele : Ntrk3<tm1Kln> neurotrophic tyrosine kinase, receptor, type 3; targeted mutation 1, Rudiger Klein
Primary Identifier  MGI:2656335 Allele Type  Targeted
Attribute String  Not Specified Gene  Ntrk3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A tyrosine to phenylalanine substitution was introduced at residue 516 (Y516F) of the Shc adaptor binding site and a floxed neo cassette was inserted into the upstream intron via homologous recombination. The neo cassette was removed by mating mutant animals to cre deleter line TgN(CMV-cre)1Cgn.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • trkC<shc>,
  • trkC<shc>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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