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Allele : Chrm1<tm1Jwe> cholinergic receptor, muscarinic 1, CNS; targeted mutation 1, Jurgen Wess

Primary Identifier  MGI:2655332 Allele Type  Targeted
Attribute String  Null/knockout Gene  Chrm1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neomycin resistance cassette replaced a 0.28 kb genomic fragment that contained the translation start site and the region coding for the first 54 amino acids of the encoded protein. Immunoprecipitation studies demonstrated that no detectable protein was present in membranes prepared from hippocampus of homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • mAChR1<->,
  • mAChR1<->,
  • M1R<->,
  • M1 -,
  • M1R<->,
  • M1 -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

43 Publication categories