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Allele : Pdgfra<tm5Sor> platelet derived growth factor receptor, alpha polypeptide; targeted mutation 5, Philippe Soriano
Primary Identifier  MGI:2656146 Allele Type  Targeted
Attribute String  Hypomorph, Inserted expressed sequence Gene  Pdgfra
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA encoding a mutated receptor consisting of point mutations encoding the tyrosine 731/742 sites was targeted into the Pdgfra locus with a loxP-flanked neomycin cassette. Western blot analysis indicated that expression of the targeted Pdgfra locus was disrupted and the mutant receptor was expressed.
  • mutations:
  • Insertion
  • synonyms:
  • alpha<PI3K>,
  • Pdgfralpha<PI3K>,
  • alpha<PI3K>,
  • Pdgfralpha<PI3K>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

13 Publication categories





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