| Primary Identifier | MGI:2657242 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hpgd |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| description | Phenotypic Similarity to Human Syndrome: Patent Ductus Arteriosus in homozygous mice (J:74466) |
| molecularNote | The gene was disrupted by replacement of sequences corresponding to amino acids 167-266 of the human protein with a PGK-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by Northern blot analysis of lung and liver RNA. |