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Allele : Iglc1<tm2Ust> immunoglobulin lambda constant 1; targeted mutation 2, Ursula Storb

Primary Identifier  MGI:2657246 Allele Type  Targeted
Attribute String  Hypomorph Gene  Iglc1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A glycine to valine substitution was introduced to amino acid 154 (G154V) via homologous recombination. A PGK-neo cassette was inserted upstream of the J lambda 1 element for positive selection. The gene targeting event was confirmed by Southern blot analysis.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Igl-C1<tm1Ust>,
  • lambda1-val,
  • V-n,
  • lambda1-val,
  • Igl-C1<tm1Ust>,
  • V-n
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories