Primary Identifier | MGI:2657246 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Iglc1 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A glycine to valine substitution was introduced to amino acid 154 (G154V) via homologous recombination. A PGK-neo cassette was inserted upstream of the J lambda 1 element for positive selection. The gene targeting event was confirmed by Southern blot analysis. |