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Publication : Changes in nuclear receptor corepressor RIP140 do not influence mitochondrial content in the cortex.

First Author  Herbst EA Year  2015
Journal  Appl Physiol Nutr Metab Volume  40
Issue  10 Pages  1086-8
PubMed ID  26360644 Mgi Jnum  J:263899
Mgi Id  MGI:6192895 Doi  10.1139/apnm-2015-0192
Citation  Herbst EA, et al. (2015) Changes in nuclear receptor corepressor RIP140 do not influence mitochondrial content in the cortex. Appl Physiol Nutr Metab 40(10):1086-8
abstractText  Changes in nuclear receptor interacting protein 140 (RIP140) influences mitochondrial content in skeletal muscle; however, the translation of these findings to the brain has not been investigated. The present study examined the impact of overexpressing and ablating RIP140 on mitochondrial content in muscle and the cortex through examining mRNA, mtDNA, and mitochondrial protein content. Our results show that changes in RIP140 expression significantly alters markers of mitochondrial content in skeletal muscle but not the brain.
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