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Allele : Thrb<tm2Df> thyroid hormone receptor beta; targeted mutation 2, Douglas Forrest

Primary Identifier  MGI:2657173 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Thrb
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of 165 bp of coding sequence with a lacZ-neo cassette via homologous recombination resulting in the fusion of the first 54 amino acids to the lacZ gene. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of RNA from the pituitary and eyes.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Thrb2<->,
  • Thrb2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories