| Primary Identifier | MGI:2657173 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Thrb |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of 165 bp of coding sequence with a lacZ-neo cassette via homologous recombination resulting in the fusion of the first 54 amino acids to the lacZ gene. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of RNA from the pituitary and eyes. |