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Allele : Otx2<tm6Asim> orthodenticle homeobox 2; targeted mutation 6, Antonio Simeone

Primary Identifier	MGI:2661065	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Otx2
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A a single loxP site was inserted upstream of exon 2 and floxed PGK-neo was inserted downstream of exon 2 via homologous recombination. Cre-mediated recombination removed the selection cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Otx2<flox>,
Otx2<flox>

earliestPublication:
Puelles E, et al. (2003) Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain. Nat Neurosci 6(5):453-60

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

17 Publication categories

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