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Allele : Igl<tm1Cgn> immunoglobulin lambda chain complex; targeted mutation 1, University of Cologne
Primary Identifier  MGI:2662343 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Igl
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  An 18 kb region between Igl-V1 and Igl-J1 was replaced with a pre-arranged VJ1 gene and a floxed ACN cassette containing a neo resistance gene and sperm-specific cre gene. The ACN cassette is excised in chimeric animals during spermatogenesis. Semiquantitative RT-PCR analysis confirmed the expression of the prearranged VJ1 insertion in splenic B cells.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • VJlambda1i,
  • VJlambda1i
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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