Primary Identifier | MGI:2663710 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Notch2 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Flanking loxP sites and a PGK-neo cassette were introduced to the exons encoding the transmembrane domains. The selection cassette was subsequently deleted by transient expression of cre recombinase in correctly targeted ES cells, leaving loxP sites flanking the sequences encoding the transmembrane domain. |