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Allele : Thpo<tm1Mwm> thrombopoietin; targeted mutation 1, Mark W Moore

Primary Identifier  MGI:2662551 Allele Type  Targeted
Attribute String  Null/knockout Gene  Thpo
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct introduces a neo cassette into the 4th exon of the gene, replacing sequences encoding 23 amino acids in the domain responsible for receptor binding and activation. mRNA was not detected in the liver and kidney of mutant animals.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • TPO-,
  • TPO-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

23 Publication categories