| Help | About | Contact Us

Allele : **Tg(PSEN1*L286V)1274Citr** transgene insertion 1274, Martin Citron

Primary Identifier	MGI:2664251	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	*Tg(PSEN1L286V)1274Citr**
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

A human PSEN1 cDNA sequence with an engineered leucine to valine mutation at residue 286 (L286V) was used for the transgene.

mutations:
Insertion

synonyms:
Tg(PSEN1-L286V)3Citr,
Tg(PSEN1-L286V)3Citr

earliestPublication:
Citron M, et al. (1997) Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat Med 3(1):67-72

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

7 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74428082

MouseMine

Allele : Tg(PSEN1*L286V)1274Citr transgene insertion 1274, Martin Citron

External Links