Primary Identifier | MGI:2664968 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Foxa3-cre)1Khk |
Strain of Origin | (DBA x C57BL/6)F1 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgenic construct consists of a 170 kb fragment containing a modified Foxa3 locus in which exon 2 has been replaced with an IRES-cre cassette. Cre activity was first detected 8.5 dpc in the anterior intestinal portal, and later in the entire gut endoderm from stomach to colon. Efficient cre-mediated recombination was demonstrated in the stomach, liver, pancreas, and colon. |