Primary Identifier | MGI:2664484 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bin1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacing the region encoding the BAR domain (part of exon 3 and all of exons 4 and 5) with a neomycin resistance cassette. Absence of gene expression was confirmed by Western blot analysis of embyronic fibrobasts derived from homozygous mutants. |