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Allele : Prkcq<tm1Litt> protein kinase C, theta; targeted mutation 1, Dan Littman
Primary Identifier  MGI:2664379 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prkcq
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The exon encoding the ATP-binding site of the kinase domain (aa 396 - 451) was replaced with a neo cassette inserted by homologous recombination. Protein was undetected in thymocytes or T cells obtained from mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PKCtheta<->,
  • PKC-Theta<->,
  • PKCtheta<->,
  • PKC-Theta<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

89 Publication categories





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