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Allele : Gjc2<tm1(EGFP)Kwi> gap junction protein, gamma 2; targeted mutation 1, Klaus Willecke

Primary Identifier  MGI:2664941 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Gjc2
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  EGFP-1 was inserted, beginning with its ATG start codon, "in frame" after the first 7 codons of the gene followed (in antisense orientation) by HPRT driven by the mouse PGK promotor. This insertion replaced the rest of the gene and 560 bp of the 3' untranslated region. Homozygous mutant mice failed to express target gene mRNA but did express EGFP mRNA.
  • mutations:
  • Insertion
  • synonyms:
  • Cx47<EGFP>,
  • Cx47<EGFP>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

16 Publication categories