Primary Identifier | MGI:2665105 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(TcrLCMV)327Sdz |
Strain of Origin | (C57BL/6 x DBA/2)F2 | Is Recombinase | false |
Is Wild Type | false |
description | Transgenic mice carry a T-cell receptor (Tcra-V2, Tcra-J TA31 / Tcrb-V8.1, Tcrb-D, Tcrb-J 2.4) specific for the gp33 protein of LCMV (lymphocytic choriomeningitis virus), H2-Db. |
molecularNote | The transgene carries both Tcra and Tcrb. Ten to twenty copies of the Tcr transgene were reported to have integrated on the same chromosome. At least two transgenic lines are known to exist. Line 327 is the representative line. The second line is 318. |