Primary Identifier | MGI:2668338 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Prdx6 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1 and 2 were replaced with a neomycin drug resistance gene and a lacZ gene. RT-PCR demonstrated the absence of mRNA in the livers of homozygotes while the absence of protein was proven by Western blot and by immunohistochemistry. |