| Primary Identifier | MGI:2668458 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Rln1 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 750 bp fragment was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded 90 carboxy terminal amino acids of the 103 amino acids that make up the C peptide and 17 amino terminal amino acids of the 25 amino acids that comprise the A chain. Northern blot analysis of ovarian RNA indicated an absence of normal transcript in homozygous mutant females. |
