Primary Identifier | MGI:2670726 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ksr1 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Sequence encoding the initiator methionine and 74 downstream amino acids encompassing 85% of the unique CA1 domain was replaced with a neomycin selection cassette. Transcript was undetected by Northern blot analysis of homozygous mutant mice. Similarly, no protein was detected in homozygotes by Western blot analysis. |