Primary Identifier | MGI:2670952 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ptx3 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced a genomic fragment containing exons 1 and 2 by homologous recombination. The deleted region encodes the initiation codon and signal peptide for secretion of the protein, so the mutation is predicted to be a null allele. |