| First Author | Shekhtmeyster P | Year | 2023 |
| Journal | Nat Biotechnol | Volume | 41 |
| Issue | 12 | Pages | 1729-1733 |
| PubMed ID | 36879007 | Mgi Jnum | J:347036 |
| Mgi Id | MGI:7618877 | Doi | 10.1038/s41587-023-01700-3 |
| Citation | Shekhtmeyster P, et al. (2023) Trans-segmental imaging in the spinal cord of behaving mice. Nat Biotechnol 41(12):1729-1733 |
| abstractText | Spinal cord circuits play crucial roles in transmitting pain, but the underlying activity patterns within and across spinal segments in behaving mice have remained elusive. We developed a wearable widefield macroscope with a 7.9-mm(2) field of view, ~3- to 4-mum lateral resolution, 2.7-mm working distance and <10-g overall weight and show that highly localized painful mechanical stimuli evoke widespread, coordinated astrocyte excitation across multiple spinal segments. |
