| Primary Identifier | MGI:2671884 | Allele Type | Chemically induced (ENU) |
| Gene | Nxn | Inheritance Mode | Recessive |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false | Project Collection | Mutagenesis for Dev. Defects |
| molecularNote | This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. A T-to-A point mutation occurs two base pairs after exon 6, resulting in alteration of a consensus splice donor sequence. RT-PCR and sequencing showed that the mutation results in aberrant splicing of the transcript. A noncomplementation test with a knockout allele confirmed that the mutation in this gene is responsible for the mutant phenotype. |
