| Primary Identifier | MGI:2674932 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pgr |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | To eliminate the translation of isoform B, the start codon of isoform B was mutated to encode leucine (ATG to CTG). A single loxP site remained in an intron after a floxed selection cassette was excised via cre mediated recombination. While isoform B was undetected by Western blot analysis of homozygous mutant uterine extracts, the presence of isoform A was confirmed. |
