Primary Identifier | MGI:2673930 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Mdm2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Single loxP sites remained flanking exons 7, 8, and 9 after the floxed puromycin selection cassette was excised from Mdm2tm1Mep via in vivo cre-mediated recombination. Western blot analysis indicated that the loxP sites did not interfere with protein expression. |