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Allele : Nod1<tm1Inoh> nucleotide-binding oligomerization domain containing 1; targeted mutation 1, Naohiro Inohara
Primary Identifier  MGI:2674231 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nod1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1 and 2 were replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded the CARD domain which is essential for Ripk2 binding and Nfkb1 activation. Transcript was undetected by RT-PCR analysis of cells obtained from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Nlrc1<->,
  • Nlrc1<->,
  • Nod1<->,
  • Nod1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

46 Publication categories

Trail: Allele




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