| Primary Identifier | MGI:2674289 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pax6 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Alternative splicing of the endogenous locus yields a transcript that includes exon 5a and encodes a protein with an additional 14 residues. Isoform-specific ablation was achieved by the replacement of exon 5a with a single loxP site. Transcript including exon 5a was undetected by RT-PCR analysis of homozygous mutant mice, which also showed the presence of the endogenous transcript that lacks exon 5a. |
