| Help | About | Contact Us

Allele : H2-Oa<tm1Lkar> histocompatibility 2, O region alpha locus; targeted mutation 1, Lars Karlsson

Primary Identifier	MGI:2675254	Allele Type	Targeted
Attribute String	Null/knockout	Gene	H2-Oa
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A 5' portion of exon 2 was replaced with a neomycin resistance gene inserted by homologous recombination. Protein was undetected in homozygous mutant splenocytes by immunoprecipitation.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
H2-Oa-,
H2-O<->,
H2-O<->,
H2-Oa-

earliestPublication:
Liljedahl M, et al. (1998) Altered antigen presentation in mice lacking H2-O. Immunity 8(2):233-43

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

14 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74445028

MouseMine