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Allele : Nat2<tm1Esim> N-acetyltransferase 2 (arylamine N-acetyltransferase); targeted mutation 1, Edith Sim

Primary Identifier  MGI:2675637 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Nat2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The endogenous locus was disrupted by the insertion of a cassette containing IRES-lacZ and floxed neo into the coding region. Absence of a functional protein was indicated by ablated acetylation of Nat2-specific substrates and by Western blot analysis of liver homogenates. Expression of lacZ was driven by the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • Nat2<->,
  • Nat2<*>-,
  • Nat2<->,
  • Nat2<*>-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

11 Publication categories