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Allele : Ern2<tm1Dron> endoplasmic reticulum to nucleus signalling 2; targeted mutation 1, David Ron

Primary Identifier  MGI:2677494 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ern2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced 2.6 kb of genomic DNA that contains exons 12 and 13 which encode amino acid residues 408-497 in the transmembrane domain. Immunoprecipitation and western blot analysis demonstrated that no detectable protein is produced from this allele in colonic mucosa.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • IRE1beta -,
  • IRE1beta -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories