| Primary Identifier | MGI:2677498 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hba-a1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin selection cassette replaced a small 295 bp fragment in the second exon of the gene. Northern blot analysis on RNA derived from homozygous embryos demonstrated that a reduced amount of alpha-globin transcript was present in comparison to wild type. The authors propose that the remaining mRNA arose from the adjacent Hba-a2 gene. |
