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Allele : Nfkb2<tm1Rsch> nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; targeted mutation 1, Roland Schmid

Primary Identifier  MGI:2675476 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfkb2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A 2.5 kb genomic fragment containing exons 1b through 9 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded the initiator methionine and a portion of the Rel homology domain. Protein was undetected in homozygous mutant mice by Western blot analysis of spleen whole-cell protein extracts and a supershift analysis of spleen nuclear extracts.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Nf-kb2<->,
  • Nf-kb2<->,
  • p52<->,
  • p52<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele