Primary Identifier | MGI:2675476 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nfkb2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 2.5 kb genomic fragment containing exons 1b through 9 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded the initiator methionine and a portion of the Rel homology domain. Protein was undetected in homozygous mutant mice by Western blot analysis of spleen whole-cell protein extracts and a supershift analysis of spleen nuclear extracts. |