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Allele : Syt7<tm1Nan> synaptotagmin VII; targeted mutation 1, Norma W Andrews

Primary Identifier  MGI:2676220 Allele Type  Targeted
Attribute String  Null/knockout Gene  Syt7
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP flanked neomycin resistance cassette replaced most of exon 4 and exon 5. In the process a stop codon was generated in exon 4 after the codon for amino acid 83. Absence of the 1.2kb mRNA for the major isoform of this gene was established by Northern blot analysis. Lack of protein product was confirmed by Western blot analysis. However, a truncated protein may be produced.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Syt VII -,
  • Syt VII -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

30 Publication categories