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Allele : Cd83<tm1Tft> CD83 antigen; targeted mutation 1, Thomas F Tedder

Primary Identifier  MGI:2676282 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd83
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  A sequence fragment extending from within exon 3 through the coding region of exon 5 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded 25 residues of the immunoglobulin-like domain and the transmembrane and cytoplasmic domains. Transcript was undetected in homozygous mutant mice by RT-PCR analysis of LPS-stimulated bone marrow-derived dendritic cells.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CD83<->,
  • CD83<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

9 Publication categories