Primary Identifier | MGI:2676282 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd83 |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A sequence fragment extending from within exon 3 through the coding region of exon 5 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded 25 residues of the immunoglobulin-like domain and the transmembrane and cytoplasmic domains. Transcript was undetected in homozygous mutant mice by RT-PCR analysis of LPS-stimulated bone marrow-derived dendritic cells. |