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Allele : Pitpna<tm1Vab> phosphatidylinositol transfer protein, alpha; targeted mutation 1, Vytas A Bankaitis

Primary Identifier  MGI:2676298 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pitpna
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 8, 9, and 10 were replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded residues 162 through 257 and has been shown to be essential for catalytic activity. Protein was undetected by Western blot analyses of homozygous mutant ES cells and mice.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • PITPalphadelta1::neo*,
  • PITPalpha-,
  • PITPalphadelta1::neo*,
  • PITPalphadelta::neo*,
  • PITPalphadelta::neo*,
  • PITPalpha-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories