| Primary Identifier | MGI:2676654 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Map3k1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A small part of the coding sequence for the regulatory domain and all of the sequence for the C-terminal catalytic domain were replaced by LacZ and a neomycin resistence gene. MEKK1 kinase activity was reduced in heterozygous ES cells and no activity was present in homozygous ES cells. |