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Allele : Map3k1<tm1Yxia> mitogen-activated protein kinase kinase kinase 1; targeted mutation 1, Ying Xia

Primary Identifier  MGI:2676654 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Map3k1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A small part of the coding sequence for the regulatory domain and all of the sequence for the C-terminal catalytic domain were replaced by LacZ and a neomycin resistence gene. MEKK1 kinase activity was reduced in heterozygous ES cells and no activity was present in homozygous ES cells.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Map3k1<deltaKD>,
  • Mekk1<deltaKD>,
  • Map3k1<deltaKD>,
  • Mekk1<deltaKD>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

32 Publication categories

Trail: Allele