| Primary Identifier | MGI:2678364 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Impdh1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A PGK-neomycin resistance gene was inserted in exon 9 together with a deletion of sequence at the end of the exon coding for amino acids 323-331. This eliminates the 2 amino acids lining the IMP binding pocket. No detectable mRNA transcripts are formed and Western blot analysis indicates that there is no gene product in thymus, lungs, or lymphocytes. |
