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Allele : Igf2<tm1Rob> insulin-like growth factor 2; targeted mutation 1, Elizabeth J Robertson

Primary Identifier  MGI:2677156 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igf2
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129S/SvEv-Gpi1<c> Is Recombinase  false
Is Wild Type  false
description  This gene is maternally imprinted and only expressed when paternally inherited. Inheritance of the maternal allele in the heterozygous state is equivalent to wild-type homozygotes where as inheritance of the paternal allele in the heterogyzous state is equivalent to knock-out homozygotes.
molecularNote  Sequences encoding part of the first coding exon were replaced with a neomycin resistance gene cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Igf-2(p-),
  • Igf-2(p-),
  • Igf2<->,
  • Igf-II(-),
  • Igf2<tm1Rob-pat>,
  • IGF2(-),
  • Igf-II(-),
  • Igf2<tm1Rob-pat>,
  • Igf2<->,
  • IGF2(-)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

62 Publication categories