| Primary Identifier | MGI:2677452 | Allele Type | Targeted |
| Attribute String | Dominant negative | Gene | Sall1 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A dominant-negative allele, recapitulating the human SALL1 1277-1278delGA mutation, was generated by inserting a stop codon and a floxed neo cassette into the exon 2. The deleted region corresponded with nt 1300-3443 of the cDNA. A truncated protein was detected by Western blot analyis of homozygous mutant embryonic tissue using an N-terminal antibody. |
