Primary Identifier | MGI:2677892 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Hif1a |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 13, 14, and 15 were flanked by single loxP sites. The floxed region encodes the C-terminal transactivation domain that is involved in response to hypoxia, Cri2 recruitment, and efficient nuclear localization. |