| Primary Identifier | MGI:2678815 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Ikbkb |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Single loxP sites flank exon 7. The floxed exon encodes amino acids 160 through 189, including serines 177 and 181, two residues of the activation loop that are essential for kinase activity. Excision of the floxed fragment results in splicing between exons 6 and 8, producing a protein that lacks kinase activity but that is incorporated into the Ikbk complex. |
