Primary Identifier | MGI:2679632 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Plcl2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was replaced with a cassette containing a neomycin resistance gene. The deleted exon encoded the pleckstrin homology domain, the X-Y domain, and the C2 domain. Protein was undetected in homozygous mutant mice by Western blot analysis of spleen extracts. |