| Primary Identifier | MGI:2679972 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Arx |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 1 and 2 were replaced with a cassette containing lacZ followed by floxed neo. The deleted sequence encodes 360 N-terminal residues which make up the octapeptide (Eh1 domain), alpha-helix 1, and approximately half of alpha-helix 2 homeodomain. Normal transcript was undetected by in situ hybridization of neural tube sections obtained from hemizygous fetuses. LacZ expression was detected. |
