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Allele : Cdkn2a<tm1Nesh> cyclin dependent kinase inhibitor 2A; targeted mutation 1, Norman E Sharpless
Primary Identifier  MGI:2677722 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdkn2a
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A premature stop codon was generated in exon 1 beta, unique to P19ARF, by cre-mediated excision of a floxed neomycin cassette, leaving the cis-regulatory elements of both P19ARF and P16INK4 intact. Loss of P19ARF and presence of P16INK4 was confirmed by western blot analysis of homozygous mutant MEFs.
  • mutations:
  • Insertion
  • synonyms:
  • Arf<->,
  • Arf<->,
  • P19<ARF>-,
  • P19<ARF>-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

14 Publication categories





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