Primary Identifier | MGI:2680653 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Kcnq1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Insertion of a neomycin resistance cassette into exon 2 disrupted the Kcnq1 gene. Northern blot analysis demonstrated that no detectable transcript was expressed in hearts of homozygous mice. |