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Allele : Ticam1<Lps2> TIR domain containing adaptor molecule 1; lipopolysaccharide 2

Primary Identifier  MGI:2679794 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Ticam1
Inheritance Mode  Codominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU mutagenesis induced the deletion of a single guanine within codon 708, resulting in a frameshift mutation. The mutation was predicted to replace 24 C-terminal residues with 11 unrelated residues. The mutation was initially detected by screening macrophages for their competence to respond to LPS.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Trif<m>,
  • Trif<m>,
  • Ticam1<->,
  • Trif<Lps2>,
  • Lps2-,
  • Lps,
  • Ticam1<M1Btlr>,
  • TRIF-,
  • Lps2,
  • Ticam1<->,
  • Lps2,
  • Trif<Lps2>,
  • Lps,
  • TRIF-,
  • Lps2-,
  • Ticam1<M1Btlr>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

311 Publication categories