Primary Identifier | MGI:2680465 | Allele Type | Chemically induced (ENU) |
Gene | Mpl | Inheritance Mode | Dominant |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | DNA sequencing of exons from genomic DNA revealed a single point mutation in the Mpl gene at codon 40. The mutation is a T-to-C transition yielding an amino acid change from a conserved cysteine to an arginine. |