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Allele : Mpl<hlb219> myeloproliferative leukemia virus oncogene; heart, lung and blood, 219

Primary Identifier  MGI:2680465 Allele Type  Chemically induced (ENU)
Gene  Mpl Inheritance Mode  Dominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  DNA sequencing of exons from genomic DNA revealed a single point mutation in the Mpl gene at codon 40. The mutation is a T-to-C transition yielding an amino acid change from a conserved cysteine to an arginine.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories